C2(-SP) 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
SDS-PAGE Gel
C2 transfected lysate
Western Blot
Lane 1: C2 transfected lysate ( 34.1 KDa).
Lane 2: Non-transfected lysate.
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-C2(-SP) full-length
Host
Human
Theoretical MW (kDa)
34.1
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-C2(-SP) antibody (H00000717-B01) by Western Blots.
SDS-PAGE Gel
C2 transfected lysate
Western Blot
Lane 1: C2 transfected lysate ( 34.1 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — C2
Entrez GeneID
717GeneBank Accession#
BC029781Protein Accession#
AAH29781Gene Name
C2
Gene Alias
CO2, DKFZp779M0311
Gene Description
complement component 2
Gene Ontology
HyperlinkGene Summary
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined
Other Designations
C3/C5 convertase|OTTHUMP00000029277|OTTHUMP00000062690|complement C2|complement component C2
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com