AZU1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Western Blot
Lane 1: AZU1 transfected lysate ( 26.9 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
AZU1 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-AZU1 full-length
Host
Human
Theoretical MW (kDa)
27.72
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-AZU1 antibody (H00000566-B01) by Western Blots.
Western Blot
Lane 1: AZU1 transfected lysate ( 26.9 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
AZU1 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — AZU1
Entrez GeneID
566GeneBank Accession#
NM_001700Protein Accession#
NP_001691Gene Name
AZU1
Gene Alias
AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC
Gene Description
azurocidin 1
Omim ID
162815Gene Ontology
HyperlinkGene Summary
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq
Other Designations
cationic antimicrobial protein 37|heparin-binding protein|neutrophil azurocidin
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Interactome
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