AZU1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human AZU1 full-length ORF ( NP_001691.1, 1 a.a. - 251 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
53.3
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — AZU1
Entrez GeneID
566GeneBank Accession#
NM_001700.3Protein Accession#
NP_001691.1Gene Name
AZU1
Gene Alias
AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC
Gene Description
azurocidin 1
Omim ID
162815Gene Ontology
HyperlinkGene Summary
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq
Other Designations
cationic antimicrobial protein 37|heparin-binding protein|neutrophil azurocidin
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Interactome
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Disease
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