AGER purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
AGER MaxPab rabbit polyclonal antibody. Western Blot analysis of AGER expression in mouse lung.
Western Blot (Tissue lysate)
AGER MaxPab rabbit polyclonal antibody. Western Blot analysis of AGER expression in human placenta.
Western Blot (Cell lysate)
AGER MaxPab rabbit polyclonal antibody. Western Blot analysis of AGER expression in A-431.
Western Blot (Cell lysate)
AGER MaxPab rabbit polyclonal antibody. Western Blot analysis of AGER expression in NIH/3T3.
Western Blot (Transfected lysate)
Western Blot analysis of AGER expression in transfected 293T cell line (H00000177-T01) by AGER MaxPab polyclonal antibody.
Lane 1: AGER transfected lysate(42.80 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human AGER protein.
Immunogen
AGER (NP_001127.1, 1 a.a. ~ 404 a.a) full-length human protein.
Sequence
MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQLVVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYSCVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGVILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (78); Rat (78)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
AGER MaxPab rabbit polyclonal antibody. Western Blot analysis of AGER expression in mouse lung.Western Blot (Tissue lysate)
AGER MaxPab rabbit polyclonal antibody. Western Blot analysis of AGER expression in human placenta.Western Blot (Cell lysate)
AGER MaxPab rabbit polyclonal antibody. Western Blot analysis of AGER expression in A-431.Western Blot (Cell lysate)
AGER MaxPab rabbit polyclonal antibody. Western Blot analysis of AGER expression in NIH/3T3.Western Blot (Transfected lysate)
Western Blot analysis of AGER expression in transfected 293T cell line (H00000177-T01) by AGER MaxPab polyclonal antibody.
Lane 1: AGER transfected lysate(42.80 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — AGER
Entrez GeneID
177GeneBank Accession#
NM_001136Protein Accession#
NP_001127.1Gene Name
AGER
Gene Alias
MGC22357, RAGE
Gene Description
advanced glycosylation end product-specific receptor
Omim ID
600214Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000029155|OTTHUMP00000029156|advanced glycosylation end product-specific receptor RAGE3|advanced glycosylation end product-specific receptor variant sRAGE1|advanced glycosylation end product-specific receptor variant sRAGE2|receptor for advanced
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Interactome
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Disease
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Publication Reference
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Human intestine and placenta exhibit tissue-specific expression of RAGE isoforms.
Katharina Schwertner, Katharina Gelles, Judith Leitner, Peter Steinberger, Claudia Gundacker, Ruben Vrticka, Karin Hoffmann-Sommergruber, Isabella Ellinger, Sabine Geiselhart.
Heliyon 2023 Jul; 9(8):e18247.
Application：WB, Human, Lung, small intestine, colon, placenta, HEK 293T, JE6-1, Caco-2, FHs 74 Int, BeWo cells.
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Human intestine and placenta exhibit tissue-specific expression of RAGE isoforms.
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