ADCY5 monoclonal antibody (M01), clone 3E6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ADCY5.
Immunogen
ADCY5 (NP_899200, 1152 a.a. ~ 1261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADCY5 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — ADCY5
Entrez GeneID
111GeneBank Accession#
NM_183357Protein Accession#
NP_899200Gene Name
ADCY5
Gene Alias
AC5
Gene Description
adenylate cyclase 5
Omim ID
600293Gene Ontology
HyperlinkGene Summary
ADCY5 belongs to the adenylate cyclase (EC 4.6.1.1) family of enzymes responsible for the synthesis of cAMP (Ludwig and Seuwen, 2002 [PubMed 12503609]).[supplied by OMIM
Other Designations
adenylate cyclase, type V
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Interactome
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Pathway
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Disease
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Publication Reference
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An adenylyl cyclase signaling pathway predicts direct dopaminergic input to vestibular hair cells.
Drescher MJ, Cho WJ, Folbe AJ, Selvakumar D, Kewson DT, Abu-Hamdan MD, Oh CK, Ramakrishnan NA, Hatfield JS, Khan KM, Anne S, Harpool EC, Drescher DG.
Neuroscience 2010 Dec; 171(4):1054.
Application:IHC, Mouse, Rat, Epithelium.
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An adenylyl cyclase signaling pathway predicts direct dopaminergic input to vestibular hair cells.
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