ADARB1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ADARB1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ADARB1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ADARB1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ADARB1
Entrez GeneID
104GeneBank Accession#
ADARB1Gene Name
ADARB1
Gene Alias
ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, RED1
Gene Description
adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)
Omim ID
601218Gene Ontology
HyperlinkGene Summary
This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq
Other Designations
ADAR2c ADAR2d|OTTHUMP00000115341|OTTHUMP00000115342|RNA editase|RNA editing deaminase 1|RNA-specific adenosine deaminase B1|adenosine deaminase acting on RNA type2a|adenosine deaminase acting on RNA type2d|adenosine deaminase acting on RNA type2g|adenosin
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Interactome
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Disease
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