ADARB1 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ADARB1 protein.
Immunogen
ADARB1 (NP_056648.1, 1 a.a. ~ 741 a.a) full-length human protein.
Sequence
MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (90)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ADARB1 MaxPab polyclonal antibody. Western Blot analysis of ADARB1 expression in human kidney.Western Blot (Cell lysate)
ADARB1 MaxPab polyclonal antibody. Western Blot analysis of ADARB1 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of ADARB1 expression in transfected 293T cell line (H00000104-T03) by ADARB1 MaxPab polyclonal antibody.
Lane 1: ADARB1 transfected lysate(81.51 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ADARB1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — ADARB1
Entrez GeneID
104GeneBank Accession#
NM_015833.2Protein Accession#
NP_056648.1Gene Name
ADARB1
Gene Alias
ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, RED1
Gene Description
adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)
Omim ID
601218Gene Ontology
HyperlinkGene Summary
This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq
Other Designations
ADAR2c ADAR2d|OTTHUMP00000115341|OTTHUMP00000115342|RNA editase|RNA editing deaminase 1|RNA-specific adenosine deaminase B1|adenosine deaminase acting on RNA type2a|adenosine deaminase acting on RNA type2d|adenosine deaminase acting on RNA type2g|adenosin
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Interactome
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Disease
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