YES1/CEN18q FISH Probe
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Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human stomach carcinoma (FFPE) stained with YES1/CEN18q FISH Probe. Human stomach carcinoma showed no YES1 gene amplification.
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: YES1
Size: Approximately 150kb
Fluorophore: Texas Red
Location: 18p11.32Probe 2
Name: CEN18q
Size: Approximately 660kb
Fluorophore: FITC
Location: 18q11.2Probe Gap
The gap between two probes is approximately 29,200 kb
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome. -
Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human stomach carcinoma (FFPE) stained with YES1/CEN18q FISH Probe. Human stomach carcinoma showed no YES1 gene amplification. -
Gene Info — YES1
Entrez GeneID
7525Gene Name
YES1
Gene Alias
HsT441, P61-YES, Yes, c-yes
Gene Description
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
Omim ID
164880Gene Ontology
HyperlinkGene Summary
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq
Other Designations
OTTHUMP00000162194|Yamaguchi sarcoma oncogene|cellular yes-1 protein|proto-oncogene tyrosine-protein kinase YES|viral oncogene yes-1 homolog 1
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