AGTR2 recombinant monoclonal antibody, clone 6C7
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: 293T whole cell lysate; Lane 2: HepG2 whole cell lysate; Lane 3: A549 whole cell lysate; Lane 4: MCF-7 whole cell lysate; Lane 5: Jurkat whole cell lysate; Lane 6: Mouse liver tissue; Lane 7: Mouse heart tissue.
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Specifications
Product Description
Rabbit recombinant monoclonal antibody raised against human and mouse AGTR2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human AGTR2.
Theoretical MW (kDa)
Calculated MW: 42 kD
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity-chromatography
Isotype
IgG
Recommend Usage
ELISA
Western Blot(1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: 293T whole cell lysate; Lane 2: HepG2 whole cell lysate; Lane 3: A549 whole cell lysate; Lane 4: MCF-7 whole cell lysate; Lane 5: Jurkat whole cell lysate; Lane 6: Mouse liver tissue; Lane 7: Mouse heart tissue.Enzyme-linked Immunoabsorbent Assay
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Gene Info — AGTR2
Entrez GeneID
186Protein Accession#
P50052Gene Name
AGTR2
Gene Alias
AT2, ATGR2, MRX88
Gene Description
angiotensin II receptor, type 2
Omim ID
300034Gene Ontology
HyperlinkGene Summary
Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5' untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame. [provided by RefSeq
Other Designations
OTTHUMP00000023878|angiotensin receptor 2
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Interactomes
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Pathways
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Diseases
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