CLEC12A (Human) Recombinant Protein
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More Files
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Enzyme-linked Immunoabsorbent Assay
Immobilized Human CLEC12A at 0.5ug (100 ul/Well) on the plate. Dose response curve for Anti-CLEC12A Antibody, hFc Tag with the EC50 of 3.7 ng/ml determined by ELISA.
Tris-Bis PAGE
Human CLEC12A on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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Specifications
Product Description
Human CLEC12A (Q5QGZ9-2, His65-Ala265) partial recombinant protein with His tag at N-terminus expressed in HEK293 cells.
Sequence
His65-Ala265
Host
Human
Theoretical MW (kDa)
24.6
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Recommend Usage
Biological Activity
ELISA
Tris-Bis PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from filtered solution in PBS, pH 7.4 (5% trehalose).
Storage Instruction
After reconstitution with deionized water to a final concentration more than 100 ug/ml, store at 4°C for 1 week. For long term storage, store at -80°C for 1 year.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human CLEC12A at 0.5ug (100 ul/Well) on the plate. Dose response curve for Anti-CLEC12A Antibody, hFc Tag with the EC50 of 3.7 ng/ml determined by ELISA.Functional Study
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Gene Info — CLEC12A
Entrez GeneID
160364Protein Accession#
Q5QGZ9-2Gene Name
CLEC12A
Gene Alias
CLL-1, CLL1, DCAL-2, MGC70602, MICL
Gene Description
C-type lectin domain family 12, member A
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq
Other Designations
C-type lectin protein CLL-1|C-type lectin superfamily|C-type lectin-like molecule-1|dendritic cell associated lectin 2|myeloid inhibitory C-type lectin-like receptor
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