


SELE (Human) Recombinant Protein

* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specifications
Product Description
Human SELE (P16581, Trp22-Pro556) partial recombinant protein with His-Avi tag at C-terminus expressed in HEK293 cells.
Sequence
Trp22-Pro556
Host
Human
Theoretical MW (kDa)
61.6
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Quality Control Testing
SEC-HPLC
SEC-HPLC
The purity of Human E-selectin is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human E-selectin on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recommend Usage
Biological Activity
ELISA
SEC-HPLC
Tris-Bis PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from filtered solution in PBS, pH 7.4 (5% trehalose).
Storage Instruction
After reconstitution with deionized water to a final concentration more than 100 ug/ml, store at 4°C for 1 week. For long term storage, store at -80°C for 1 year.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human E-Selectin, His Tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-E-Selectin Antibody, hFc Tag with the EC50 of 2.3 ng/ml determined by ELISA.Functional Study
-
Gene Info — SELE
Entrez GeneID
6401Protein Accession#
P16581Gene Name
SELE
Gene Alias
CD62E, ELAM, ELAM1, ESEL, LECAM2
Gene Description
selectin E
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq
Other Designations
OTTHUMP00000032745|endothelial adhesion molecule 1|leukocyte endothelial cell adhesion molecule 2
-
Interactomes
-
Pathways
-
Diseases
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com