GRIN1 (Human) Recombinant Protein (Q01)
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More Files
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Specifications
Product Description
Human GRIN1 partial ORF ( NP_015566, 21 a.a. - 120 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GRIN1
Entrez GeneID
2902GeneBank Accession#
NM_007327Protein Accession#
NP_015566Gene Name
GRIN1
Gene Alias
NMDA1, NMDAR1, NR1
Gene Description
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Omim ID
138249Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
N-methyl-D-aspartate receptor channel, subunit zeta-1|NMDA receptor 1|OTTHUMP00000022678|glutamate [NMDA] receptor subunit zeta 1
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Target Molecular-Based Neuroactivity Screening and Analysis of Panax ginseng by Affinity Ultrafiltration, UPLC-QTOF-MS and Molecular Docking.
Yu L, Wei F, Liang J, Ren G, Liu X, Wang CZ, Yuan J, Zeng J, Luo Y, Bi Y, Yuan CS.
The American Journal of Chinese Medicine 2019 Sep; 47(6):1345.
Application：UPLC-QTOF-MS, Recombinant protein.
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Target Molecular-Based Neuroactivity Screening and Analysis of Panax ginseng by Affinity Ultrafiltration, UPLC-QTOF-MS and Molecular Docking.
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