Products

Western Blot (Transfected lysate)

Western Blot analysis of DVL1 expression in transfected 293T cell line (H00001855-T02) by DVL1 MaxPab polyclonal antibody.

Lane 1: DVL1 transfected lysate(47.70 KDa).
Lane 2: Non-transfected lysate.

In situ Proximity Ligation Assay (Cell)

Proximity Ligation Analysis of protein-protein interactions between DVL1 and CTNNB1. HeLa cells were stained with anti-DVL1 rabbit purified polyclonal 1:1200 and anti-CTNNB1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Entrez GeneID

1855

GeneBank Accession#

NM_182779

Protein Accession#

NP_877580.1

Gene Name

DVL1

Gene Alias

DVL, MGC54245

Gene Description

dishevelled, dsh homolog 1 (Drosophila)

Omim ID

601365

Gene Ontology

Hyperlink

Gene Summary

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq

Other Designations

OTTHUMP00000003104|dishevelled 1|dishevelled 1 (homologous to Drosophila dsh)