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Immunofluorescence

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

CDH17

Gene Alias

CDH16, FLJ26931, HPT-1, HPT1, MGC138218, MGC142024

Gene Description

cadherin 17, LI cadherin (liver-intestine)

Omim ID

Gene Ontology

Gene Summary

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Other Designations

HPT-1 cadherin|LI cadherin|cadherin 17|cadherin-16|human intestinal peptide-associated transporter HPT-1|human peptide transporter 1|liver-intestine cadherin