APC 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
APC transfected lysate.
Western Blot
Lane 1: APC transfected lysate ( 312.73 KDa)
Lane 2: Non-transfected lysate.
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Specifications
Transfected Cell Line
293T
Plasmid
pCMV-APC full-length
Host
Human
Theoretical MW (kDa)
312.73
Interspecies Antigen Sequence
Mouse (90); Rat (90)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-APC antibody (H00000324-D01P) by Western Blots.
SDS-PAGE Gel
APC transfected lysate.
Western Blot
Lane 1: APC transfected lysate ( 312.73 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — APC
Entrez GeneID
324GeneBank Accession#
BC111591Protein Accession#
AAI11592.1Gene Name
APC
Gene Alias
BTPS2, DP2, DP2.5, DP3, GS
Gene Description
adenomatous polyposis coli
Gene Ontology
HyperlinkGene Summary
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq
Other Designations
adenomatosis polyposis coli tumor suppressor
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Interactomes
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Pathways
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Diseases
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