IL4 (Human) Recombinant Protein
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3 ug SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Result of bioactivity analysis
Result of bioactivity analysis
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Specification
Product Description
Human IL4 (NP_000580, 25 - 153 a.a.) partial length recombinant protein expressed in Escherichia coli expression system
This product with activity data is belong to bioactive protein.Host
Escherichia coli
Theoretical MW (kDa)
15
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 95% by SDS-PAGE
Endotoxin Level
< 1 EU/ug
Activity
Human IL-4 stimulates cell proliferation of the TF-1 human erythroleukemic cells. The ED50 range ≤ 0.6 ng/mL.
Quality Control Testing
SDS-PAGE Stained with Coomassie Blue
3 ug SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Recommend Usage
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (10% glycerol)
Storage Instruction
Store at 4°C for one week. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
Result of bioactivity analysis
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Applications
SDS-PAGE
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Gene Info — IL4
Entrez GeneID
3565Protein Accession#
P05112Gene Name
IL4
Gene Alias
BCGF-1, BCGF1, BSF1, IL-4, MGC79402
Gene Description
interleukin 4
Omim ID
147780Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
B cell growth factor 1|B_cell stimulatory factor 1|lymphocyte stimulatory factor 1
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