MESP2 monoclonal antibody (M03), clone 1E11
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Specifications
Product Description
Mouse monoclonal antibody raised against a full length recombinant MESP2.
Immunogen
MESP2 (XP_085261, 2 a.a. ~ 125 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AQSPPPQSLLGHDHWIFAQGWGWAGHWDSTSPASSSDSSGSCPCDGARGLPQPQPPSCSSRAAEAAATTPRRARTGPAGGQRQSASEREKLRMRTLARALHELRRFLPPSLAPAGQSLTKIETL*
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — MESP2
Entrez GeneID
145873GeneBank Accession#
XM_085261Protein Accession#
XP_085261Gene Name
MESP2
Gene Alias
SCDO2, bHLHc6
Gene Description
mesoderm posterior 2 homolog (mouse)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02). [provided by RefSeq
Other Designations
mesoderm posterior 2 homolog
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