MTMR2 monoclonal antibody (M03), clone 4G6
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More Files
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Western Blot (Cell lysate)
MTMR2 monoclonal antibody (M03), clone 4G6. Western Blot analysis of MTMR2 expression in PC-12 ( Cat # L012V1 ).
Western Blot (Cell lysate)
MTMR2 monoclonal antibody (M03), clone 4G6 Western Blot analysis of MTMR2 expression in HeLa ( Cat # L013V1 ).
Western Blot (Transfected lysate)
Western Blot analysis of MTMR2 expression in transfected 293T cell line by MTMR2 monoclonal antibody (M03), clone 4G6.
Lane 1: MTMR2 transfected lysate(66 KDa).
Lane 2: Non-transfected lysate.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MTMR2 is approximately 0.3ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.3 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MTMR2.
Immunogen
MTMR2 (NP_057240, 5 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SSCESLGSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPDLRVLRESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGA
Host
Mouse
Reactivity
Human, Rat
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.3 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MTMR2 monoclonal antibody (M03), clone 4G6. Western Blot analysis of MTMR2 expression in PC-12 ( Cat # L012V1 ).Western Blot (Cell lysate)
MTMR2 monoclonal antibody (M03), clone 4G6 Western Blot analysis of MTMR2 expression in HeLa ( Cat # L013V1 ).Western Blot (Transfected lysate)
Western Blot analysis of MTMR2 expression in transfected 293T cell line by MTMR2 monoclonal antibody (M03), clone 4G6.
Lane 1: MTMR2 transfected lysate(66 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MTMR2 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — MTMR2
Entrez GeneID
8898GeneBank Accession#
NM_016156Protein Accession#
NP_057240Gene Name
MTMR2
Gene Alias
CMT4B, CMT4B1, KIAA1073
Gene Description
myotubularin related protein 2
Gene Ontology
HyperlinkGene Summary
This gene is a member of the myotubularin family. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
Other Designations
myotubularin-related protein 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Dlg1, Sec8, and Mtmr2 Regulate Membrane Homeostasis in Schwann Cell Myelination.
Bolis A, Coviello S, Visigalli I, Taveggia C, Bachi A, Chishti AH, Hanada T, Quattrini A, Previtali SC, Biffi A, Bolino A.
The Journal of Neuroscience 2009 Jul; 29(27):8858.
Application：WB, Rat, Nerve, Schwann cells.
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Dlg1, Sec8, and Mtmr2 Regulate Membrane Homeostasis in Schwann Cell Myelination.
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