ACOX2 monoclonal antibody (M01), clone 1D1

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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ACOX2.
Immunogen
ACOX2 (NP_003491, 582 a.a. ~ 681 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HGILTNSGDFLHDAFLSGAQVDMARTAYLDLLRLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFQWAQKSPTNTQENPAYEEYIRPLLQSWRSKL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (83)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ACOX2 expression in transfected 293T cell line by ACOX2 monoclonal antibody (M01), clone 1D1.
Lane 1: ACOX2 transfected lysate(77 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ACOX2 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — ACOX2
Entrez GeneID
8309GeneBank Accession#
NM_003500Protein Accession#
NP_003491Gene Name
ACOX2
Gene Alias
BCOX, BRCACOX, BRCOX, THCCox
Gene Description
acyl-Coenzyme A oxidase 2, branched chain
Omim ID
601641Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq
Other Designations
Peroxisomal branched chain acyl-CoA oxidase|THCA-CoA oxidase|Trihydroxycoprostanoyl-CoA oxidase
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Interactome
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Pathway
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Disease
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