RFC1 monoclonal antibody (M01), clone 3F8
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RFC1 is approximately 0.3ng/ml as a capture antibody.
Western Blot detection against Immunogen (37.51 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RFC1.
Immunogen
RFC1 (AAH51786, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPSKKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISET
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (75); Rat (77)
Isotype
IgG3 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.51 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RFC1 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — RFC1
Entrez GeneID
5981GeneBank Accession#
BC051786Protein Accession#
AAH51786Gene Name
RFC1
Gene Alias
A1, MGC51786, MHCBFB, PO-GA, RECC1, RFC, RFC140
Gene Description
replication factor C (activator 1) 1, 145kDa
Omim ID
102579Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability. [provided by RefSeq
Other Designations
MHC binding factor, beta|replication factor C (activator 1) 1 (145kD)|replication factor C large subunit|replication factor C1
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Interactome
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Pathway
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Disease
- Abnormalities
- Abruptio Placentae
- Adenocarcinoma
- Adenoma
- Alcoholism
- Alzheimer disease
- Anemia
- Aneuploidy
- Arthritis
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