NR4A2 monoclonal antibody (M19), clone 1D9

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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant NR4A2.
Immunogen
NR4A2 (NP_006177, 147 a.a. ~ 250 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPS*
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.55 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — NR4A2
Entrez GeneID
4929GeneBank Accession#
NM_006186Protein Accession#
NP_006177Gene Name
NR4A2
Gene Alias
HZF-3, NOT, NURR1, RNR1, TINUR
Gene Description
nuclear receptor subfamily 4, group A, member 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
NGFI-B/nur77 beta-type transcription factor homolog|T-cell nuclear receptor NOT|intermediate-early receptor protein|nur related protein-1, human homolog of|orphan nuclear receptor NURR1|transcriptionally inducible nuclear receptor related 1
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Interactome
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Disease
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