Products

Western Blot (Recombinant protein)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunoperoxidase of monoclonal antibody to GSK3B on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml]

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged GSK3B is approximately 3ng/ml as a capture antibody.

ELISA

In situ Proximity Ligation Assay (Cell)

Proximity Ligation Analysis of protein-protein interactions between SMAD1 and GSK3B. HeLa cells were stained with anti-SMAD1 rabbit purified polyclonal 1:1200 and anti-GSK3B mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Immunofluorescence

Immunofluorescence of monoclonal antibody to GSK3B on HeLa cell . [antibody concentration 10 ug/ml]

Entrez GeneID

2932

GeneBank Accession#

NM_002093

Protein Accession#

NP_002084

Gene Name

GSK3B

Gene Alias

-

Gene Description

glycogen synthase kinase 3 beta

Omim ID

605004

Gene Ontology

Hyperlink

Gene Summary

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene

Other Designations

GSK3beta isoform|glycogen synthase kinase-3 beta