Products

Antibody Production

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

BMPR1A

Gene Alias

10q23del, ACVRLK3, ALK3, CD292

Gene Description

bone morphogenetic protein receptor, type IA

Omim ID

Gene Ontology

Gene Summary

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq

Other Designations

OTTHUMP00000020014|activin A receptor, type II-like kinase 3