AHSG monoclonal antibody (M01), clone 5D8

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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a full length recombinant AHSG.
Immunogen
AHSG (AAH48198.1, 19 a.a. ~ 367 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
APHGPGLIYRQPNCDDPETEEAALVAIDYINQNLPWGYKHTLNQIDEVKVWPQQPSGELFEIEIDTLETTCHVLDPTPVARCSVRQLKEHAVEGDCDFQLLKLDGKFSVVYAKCDSSPDSAEDVRKVCQDCPLLAPLNDTRVVHAAKAALAAFNAQNNGSNFQLEEISRAQLVPLPPSTYVEFTVSGTDCVAKEATEAAKCNLLAEKQYGFCKATLSEKLGGAEVAVTCTVFQTQPVTSQPQPEGANEAVPTPVVDPDAPPSPPLGAPGLPPAGSPPDSHVLLAAPPGHQLHRAHYDLRHTFMGVVSLGSPSGEVSHPRKTRTVVQPSVGAAAGPVVPPCPGRIRHFKV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (57)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (64.13 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged AHSG is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — AHSG
Entrez GeneID
197GeneBank Accession#
BC048198Protein Accession#
AAH48198.1Gene Name
AHSG
Gene Alias
A2HS, AHS, FETUA, HSGA
Gene Description
alpha-2-HS-glycoprotein
Omim ID
138680Gene Ontology
HyperlinkGene Summary
Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq
Other Designations
Alpha-2HS-glycoprotein|fetuin-A
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Interactomes
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Diseases
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Publication Reference
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A proteomics approach to identify changes in protein profiles in serum of Familial Adenomatous Polyposis patients.
Quaresima B, Crugliano T, Gaspari M, Faniello MC, Cosimo P, Valanzano R, Genuardi M, Cannataro M, Veltri P, Baudi F, Doldo P, Cuda G, Venuta S, Costanzo F.
Cancer Letters 2008 Jul; 272(1):40.
Application:WB, Human, Serum from patients with Familial adenomatous polyposis.
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A proteomics approach to identify changes in protein profiles in serum of Familial Adenomatous Polyposis patients.
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