CHMP7 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human CHMP7 full-length ORF ( NP_689485.1, 1 a.a. - 453 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MWSPEREAEAPAGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLVLSHSRRQGVVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMASVDSSWISWGVGVFLLKPLKWTLSNMLGDNKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISDAELEAELEKLSLSEGGLVPSSKSPKRQLEPTLKPL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
77.3
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CHMP7
Entrez GeneID
91782GeneBank Accession#
NM_152272.2Protein Accession#
NP_689485.1Gene Name
CHMP7
Gene Alias
MGC29816
Gene Description
CHMP family, member 7
Omim ID
611130Gene Ontology
HyperlinkGene Summary
O
Other Designations
OTTHUMP00000162592
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Interactomes
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Diseases
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Publication Reference
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CHMP2B promotes CHMP7 mediated nuclear pore complex injury in sporadic ALS.
Olivia Keeley, Emma Mendoza, Druv Menon, Alyssa N Coyne.
Acta Neuropathologica Communications 2024 Dec; 12(1):199.
Application：IS, Human, iPSNs.
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CHMP2B promotes CHMP7 mediated nuclear pore complex injury in sporadic ALS.
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