CNR1 monoclonal antibody (M01), clone 2F9

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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant CNR1.
Immunogen
CNR1 (NP_057167, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMV
Host
Mouse
Reactivity
Human, Rat
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CNR1 monoclonal antibody (M01), clone 2F9. Western Blot analysis of CNR1 expression in rat testis.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CNR1 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — CNR1
Entrez GeneID
1268GeneBank Accession#
NM_016083Protein Accession#
NP_057167Gene Name
CNR1
Gene Alias
CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR
Gene Description
cannabinoid receptor 1 (brain)
Omim ID
114610Gene Ontology
HyperlinkGene Summary
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016838|OTTHUMP00000016839|OTTHUMP00000016840|central cannabinoid receptor
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Functional omics of ORP7 in primary endothelial cells.
Juuso H Taskinen, Minna Holopainen, Hanna Ruhanen, Miesje van der Stoel, Reijo Käkelä, Elina Ikonen, Salla Keskitalo, Markku Varjosalo, Vesa M Olkkonen.
BMC Biology 2024 Dec; 22(1):292.
Application:WB, Human, HUVECs cell line.
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Functional omics of ORP7 in primary endothelial cells.
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