AGER polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extract from A-549 (lane 1) and CHO cells (lane 2) (5 ug/lane), using AGER polyclonal antibody (Cat # PAB8461).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AGER.
Immunogen
A synthetic peptide corresponding to human AGER.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of extract from A-549 (lane 1) and CHO cells (lane 2) (5 ug/lane), using AGER polyclonal antibody (Cat # PAB8461). -
Gene Info — AGER
Entrez GeneID
177Gene Name
AGER
Gene Alias
MGC22357, RAGE
Gene Description
advanced glycosylation end product-specific receptor
Omim ID
600214Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000029155|OTTHUMP00000029156|advanced glycosylation end product-specific receptor RAGE3|advanced glycosylation end product-specific receptor variant sRAGE1|advanced glycosylation end product-specific receptor variant sRAGE2|receptor for advanced
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Interactome
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Disease
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Publication Reference
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Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface.
Schmidt AM, Vianna M, Gerlach M, Brett J, Ryan J, Kao J, Esposito C, Hegarty H, Hurley W, Clauss M, et al..
The Journal of Biological Chemistry 1992 Jul; 267(21):14987.
Application：Func, IEM, IF, WB-Ce, WB-Re, Bovine, Bovine aortic endothelial cells, Purified proteins.
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Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.
Neeper M, Schmidt AM, Brett J, Yan SD, Wang F, Pan YC, Elliston K, Stern D, Shaw A.
The Journal of Biological Chemistry 1992 Jul; 267(21):14998.
Application：IF, WB-Tr, Human, HEK 293 cells.
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Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface.
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