MYBL2 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MYBL2.
Immunogen
A synthetic peptide corresponding to human MYBL2.
Sequence
C-QEKARQLLGRLKPSH
Host
Goat
Theoretical MW (kDa)
78.8
Reactivity
Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
MYBL2 polyclonal antibody (Cat # PAB6908) (0.1 ug/mL) staining of rat stomach lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MYBL2
Entrez GeneID
4605Protein Accession#
NP_002457.1Gene Name
MYBL2
Gene Alias
B-MYB, BMYB, MGC15600
Gene Description
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
Omim ID
601415Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined. [provided by RefSeq
Other Designations
MYB-related protein B|OTTHUMP00000031719|v-myb avian myeloblastosis viral oncogene homolog-like 2
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Interactome
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Disease
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Publication Reference
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A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility.
Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, Barut B, Freedman M, Lee C, Spitsbergen J, Neuberg D, Weber G, Golub TR, Glickman JN, Kutok JL, Aster JC, Zon LI.
PNAS 2005 Sep; 102(37):13194.
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A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility.
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