FOXC2 polyclonal antibody
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More Files
- More Functions
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FOXC2.
Immunogen
A synthetic peptide corresponding to C-terminus of human FOXC2.
Sequence
RHAAPYSYDCTKY
Host
Goat
Theoretical MW (kDa)
53.7
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:8000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
FOXC2 polyclonal antibody (Cat # PAB6426) staining (1 ug/mL) of human breast cancer lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
FOXC2 polyclonal antibody (Cat # PAB6426, 2 ug/mL) staining of paraffin embedded human breast cancer. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FOXC2
Entrez GeneID
2303Protein Accession#
NP_005242.1Gene Name
FOXC2
Gene Alias
FKHL14, LD, MFH-1, MFH1
Gene Description
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
Gene Ontology
HyperlinkGene Summary
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues. [provided by RefSeq
Other Designations
MFH-1,mesenchyme forkhead 1|forkhead box C2|forkhead, Drosophila, homolog-like 14|forkhead-like 14
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Interactome
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Disease
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Publication Reference
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Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome.
Dagenais SL, Hartsough RL, Erickson RP, Witte MH, Butler MG, Glover TW.
Gene Expression Patterns 2004 Oct; 4(6):611.
Application:IF, IHC-P, Mouse, Mouse embryos.
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Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome.
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