CSF1R (phospho Y561) polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of Lane 1: PMA treated HepG2 cells, Lane 2: antigen-specific peptide treated HepG2 cells with CSF1R (phospho Y561) polyclonal antibody (Cat# PAB29277) at 1:500-1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain tissue with CSF1R (phospho Y561) polyclonal antibody (Cat# PAB29277) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CSF1R.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y561 of human CSF1R.
Host
Rabbit
Theoretical MW (kDa)
130
Reactivity
Human, Mouse
Specificity
CSF1R (phospho Y561) polyclonal antibody detects endogenous levels of human CSF1R only when phosphorylated at tyrosine 561.
Form
Liquid
Purification
Affinity Chromatography
Recommend Usage
Immunohistochemistry (1:50~1:100)
Western Blot (1:500~1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane 1: PMA treated HepG2 cells, Lane 2: antigen-specific peptide treated HepG2 cells with CSF1R (phospho Y561) polyclonal antibody (Cat# PAB29277) at 1:500-1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain tissue with CSF1R (phospho Y561) polyclonal antibody (Cat# PAB29277) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution. -
Gene Info — CSF1R
Entrez GeneID
1436Protein Accession#
P07333Gene Name
CSF1R
Gene Alias
C-FMS, CD115, CSFR, FIM2, FMS
Gene Description
colony stimulating factor 1 receptor
Omim ID
164770Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq
Other Designations
CD115 antigen|FMS proto-oncogene|McDonough feline sarcoma viral (v-fms) oncogene homolog|macrophage colony stimulating factor I receptor|soluble CSF1R variant 1
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Interactome
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Disease
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