EPOR polyclonal antibody

Catalog # PAB18350

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Price

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Size:100 ug
Price: USD $ 346.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of extracts from COS-7 cells, treated with EPO (20 U/mL, 15 mins), using EPOR polyclonal antibody (Cat # PAB18350).
Peptide "+" means "peptide blocking".

Immunofluorescence
Application

Immunofluorescence

Immunofluorescence analysis of HeLa cells, using EPOR polyclonal antibody (Cat # PAB18350).
Peptide "+" means "peptide blocking".

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against synthetic peptide of EPOR.

    Immunogen

    A synthetic peptide corresponding to residues surrounding Y368 of human EPOR.

    Host

    Rabbit

    Reactivity

    Human, Mouse, Rat

    Specificity

    This antibody is specific to EPOR.

    Form

    Liquid

    Purification

    Affinity purification

    Concentration

    1 mg/mL

    Recommend Usage

    Western Blot (1:500-1:1000)
    Immunofluorescence (1:500-1:1000)
    ELISA (1:5000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of extracts from COS-7 cells, treated with EPO (20 U/mL, 15 mins), using EPOR polyclonal antibody (Cat # PAB18350).
    Peptide "+" means "peptide blocking".

    Immunofluorescence

    Immunofluorescence analysis of HeLa cells, using EPOR polyclonal antibody (Cat # PAB18350).
    Peptide "+" means "peptide blocking".

    Enzyme-linked Immunoabsorbent Assay

  • Gene Info — EPOR

    Entrez GeneID

    2057

    Protein Accession#

    P19235

    Gene Name

    EPOR

    Gene Alias

    MGC138358

    Gene Description

    erythropoietin receptor

    Omim ID

    133100 133171

    Gene Ontology

    Hyperlink

    Gene Summary

    The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. [provided by RefSeq

    Other Designations

    -

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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