SOX2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of SOX2 in mouse brain lysate with SOX2 polyclonal antibody at 0.5 ug/mL (Cat # PAB12025).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SOX2.
Immunogen
A synthetic peptide corresponding to amino acids 1-100 of human SOX2.
Host
Rabbit
Reactivity
Chicken, Human, Mouse, Sheep, Xenopus, Zebra fish
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Flow Cytometry (1:100)
Immunocytochemistry (1:125-1:250)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:125-1:250)
Western Blot (0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SOX2 in mouse brain lysate with SOX2 polyclonal antibody at 0.5 ug/mL (Cat # PAB12025).Immunohistochemistry
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Gene Info — SOX2
Entrez GeneID
6657Protein Accession#
P48431Gene Name
SOX2
Gene Alias
ANOP3, MCOPS3, MGC2413
Gene Description
SRY (sex determining region Y)-box 2
Gene Ontology
HyperlinkGene Summary
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq
Other Designations
SRY-related HMG-box gene 2|sex-determining region Y-box 2|transcription factor SOX2
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Interactome
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Disease
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