MYC monoclonal antibody, clone 2B2
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of MYC.
Immunogen
A synthetic peptide corresponding to amino acids 408-420 at C-terminus of human MYC.
Host
Mouse
Reactivity
Human
Specificity
It recognizes MYC and MYC tagged fusion proteins.
Form
Liquid
Purification
Affinity purification
Isotype
IgG1
Recommend Usage
Western blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western Blot (Recombinant protein)
Western blot analysis of Myc tagged rice protein A in leaf (Lane 1) and panicle (Lane 2) with MYC monoclonal antibody, clone 2B2 (Cat # MAB9906) at 1:1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MYC
Entrez GeneID
4609GeneBank Accession#
NM_002467Protein Accession#
NP_002458.2Gene Name
MYC
Gene Alias
bHLHe39, c-Myc
Gene Description
v-myc myelocytomatosis viral oncogene homolog (avian)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq
Other Designations
avian myelocytomatosis viral oncogene homolog|myc proto-oncogene protein|v-myc avian myelocytomatosis viral oncogene homolog
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Interactome
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Pathway
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Disease
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