SNAI2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SNAI2 partial ORF ( NP_003059, 97 a.a. - 169 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KDHSGSESPISDEEERLQSKLSDPHAIEAEKFQCNLCNKTYSTFSGLAKHKQLHCDAQSRKSFSCKYCDKEYV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
33.77
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SNAI2
Entrez GeneID
6591GeneBank Accession#
NM_003068Protein Accession#
NP_003059Gene Name
SNAI2
Gene Alias
MGC10182, SLUG, SLUGH1, WS2D
Gene Description
snail homolog 2 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq
Other Designations
OTTHUMP00000195093|neural crest transcription factor SLUG|slug (chicken homolog), zinc finger protein|slug homolog, zinc finger protein|snail 2
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Interactome
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Disease
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