HLA-DMA MaxPab rabbit polyclonal antibody (D01)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human HLA-DMA protein.
Immunogen
HLA-DMA (NP_006111.2, 1 a.a. ~ 261 a.a) full-length human protein.
Sequence
MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGD
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in mouse kidney.Western Blot (Tissue lysate)
HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in human stomach.Western Blot (Cell lysate)
HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in HeLa.Western Blot (Cell lysate)
HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of HLA-DMA expression in transfected 293T cell line (H00003108-T01) by HLA-DMA MaxPab polyclonal antibody.
Lane 1: HLA-DMA transfected lysate(29.20 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of HLA-DMA transfected lysate using anti-HLA-DMA MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with HLA-DMA purified MaxPab mouse polyclonal antibody (B01P) (H00003108-B01P). -
Gene Info — HLA-DMA
Entrez GeneID
3108GeneBank Accession#
NM_006120Protein Accession#
NP_006111.2Gene Name
HLA-DMA
Gene Alias
D6S222E, DMA, HLADM, RING6
Gene Description
major histocompatibility complex, class II, DM alpha
Omim ID
142855Gene Ontology
HyperlinkGene Summary
HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq
Other Designations
OTTHUMP00000029242|OTTHUMP00000062997|class II histocompatibility antigen, M alpha chain
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Interactome
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Pathway
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Disease
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