CLPS (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CLPS full-length ORF ( AAH07061, 1 a.a. - 112 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MEKILILLLVALSVAYAAPGPRGIIINLENGELCMNSAQCKSNCCQHSSALGLARCTSMASENSECSVKTLYGIYYKCPCERGLTCEGDKTIVGSITNTNFGICHDAGRSKQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
38.06
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CLPS
Entrez GeneID
1208GeneBank Accession#
BC007061Protein Accession#
AAH07061Gene Name
CLPS
Gene Alias
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Gene Description
colipase, pancreatic
Omim ID
120105Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. [provided by RefSeq
Other Designations
OTTHUMP00000016271|colipase|pancreatic colipase preproprotein
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Interactome
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Disease
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