ASCL1 (Human) Recombinant Protein (Q03)
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More Files
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Specification
Product Description
Human ASCL1 partial ORF (NP_004307.2, 76 a.a. - 170 a.a.) recombinant protein with GST tag at N-terminal.
Sequence
GGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRAL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.19
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ASCL1
Entrez GeneID
429GeneBank Accession#
NM_004316.2Protein Accession#
NP_004307.2Gene Name
ASCL1
Gene Alias
ASH1, HASH1, MASH1, bHLHa46
Gene Description
achaete-scute complex homolog 1 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq
Other Designations
achaete scute protein|achaete-scute complex homolog 1|achaete-scute complex-like 1
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Interactome
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Disease
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