MERTK/CEN2q FISH Probe
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Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human lung adenocarcinoma (FFPE) stained with MER/CEN2q FISH Probe. Human lung adenocarcinoma showed no MER gene amplification.
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human renal cell carcinoma (FFPE) stained with MER/CEN2q FISH Probe. Human renal cell carcinoma showed no MER gene amplification.
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human hepatocellular carcinoma (FFPE) stained with MER/CEN2q FISH Probe. Human hepatocellular carcinoma showed no MER gene amplification.
Hybridization position of the probes on the chromosome:
Hybridization position of the probes on the chromosome:
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: MERTK
Size: Approximately 290kb
Fluorophore: TexRed
Location: 2q13Probe 2
Name: CEN2q
Size: Approximately 580kb
Fluorophore: FITC
Location: 2q11.2Probe Gap
The gap between two probes is approximately 13560 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome:
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Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human lung adenocarcinoma (FFPE) stained with MER/CEN2q FISH Probe. Human lung adenocarcinoma showed no MER gene amplification.Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human renal cell carcinoma (FFPE) stained with MER/CEN2q FISH Probe. Human renal cell carcinoma showed no MER gene amplification.Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human hepatocellular carcinoma (FFPE) stained with MER/CEN2q FISH Probe. Human hepatocellular carcinoma showed no MER gene amplification. -
Gene Info — MERTK
Entrez GeneID
10461Gene Name
MERTK
Gene Alias
MER, MGC133349, RP38, c-mer
Gene Description
c-mer proto-oncogene tyrosine kinase
Gene Ontology
HyperlinkGene Summary
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq
Other Designations
MER receptor tyrosine kinase|STK kinase
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Interactome
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Disease
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