CAMK2G polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CAMK2G.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 316-346 at C-terminus of human CAMK2G.
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
The CAMK2G polyclonal antibody (Cat # PAB2772) is used in Western blot to detect CAMK2G in mouse heart tissue lysate.Western Blot (Cell lysate)
Western blot analysis of CAMK2G polyclonal antibody (Cat # PAB2772) in K-562 cell line lysates (35 ug/lane). CAMK2G (arrow) was detected using the purified polyclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with CAMK2G polyclonal antibody (Cat # PAB2772) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. -
Gene Info — CAMK2G
Entrez GeneID
818Protein Accession#
NP_751911;O15378Gene Name
CAMK2G
Gene Alias
CAMK, CAMK-II, CAMKG, FLJ16043, MGC26678
Gene Description
calcium/calmodulin-dependent protein kinase II gamma
Omim ID
602123Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Six alternatively spliced variants that encode six different isoforms have been characterized to date. Additional alternative splice variants that encode different isoforms have been described, but their full-length nature has not been determined. [provided by RefSeq
Other Designations
CaM kinase II|OTTHUMP00000019843|OTTHUMP00000019844|calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma
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Interactome
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Pathway
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Disease
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Publication Reference
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Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II.
Breen MA, Ashcroft SJ.
Biochemical and Biophysical Research Communications 1997 Jul; 236(2):473.
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Identification of novel human tumor cell-specific CaMK-II variants.
Tombes RM, Krystal GW.
Biochimica et Biophysica acta 1997 Mar; 1355(3):281.
Application:WB-Ce, WB-Ti, Human, Rat, Brain, LAN5, MCF10 A, MCF7 cells.
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Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II.
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