SOX2 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
The tissue lysate derived from embryonic mouse brain immunoblotted by SOX2 polyclonal antibody (Cat # PAB12735) at 1 : 500.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SOX2.
Immunogen
A synthetic peptide corresponding to N-terminus of human SOX2.
Host
Rabbit
Theoretical MW (kDa)
35
Reactivity
Human, Mouse, Rat
Specificity
This antibody recognizes ~35 KDa of human SOX2.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (0.1-1 ug/mL)
ELISA (0.01-0.1 ug/mL)
Immunoprecipitation (2-5 ug/mL)
Immunohistochemistry (2-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In TBS, pH 7.2 (BSA, 10% Proclin300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
The tissue lysate derived from embryonic mouse brain immunoblotted by SOX2 polyclonal antibody (Cat # PAB12735) at 1 : 500.Immunohistochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SOX2
Entrez GeneID
6657Gene Name
SOX2
Gene Alias
ANOP3, MCOPS3, MGC2413
Gene Description
SRY (sex determining region Y)-box 2
Gene Ontology
HyperlinkGene Summary
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq
Other Designations
SRY-related HMG-box gene 2|sex-determining region Y-box 2|transcription factor SOX2
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Interactome
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Disease
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Publication Reference
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Sox-2 is expressed by neural progenitors and astroglia in the adult rat brain.
Komitova M, Eriksson PS.
Neuroscience Letters 2004 Oct; 369(1):24.
Application：IHC, Rat, Rat brains.
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Sox-2 is expressed by neural progenitors and astroglia in the adult rat brain.
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