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BIOtech
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MAPK14 (phospho Y322) Peptide

  • Catalog # : P1573
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  • Specification
  • Product Description:
  • This synthetic peptide is phosphorlated on Y322 of human MAPK14 and is used as the immunogen for PAB1674.
  • Sequence:
  • Amino acid near Y322 of Human MAPK14
  • Form:
  • Lyophilized with 100% acetonitrile
  • Storage Buffer:
  • Reconstitute with 100 uL deionized water for a final concentration of 1 mg/mL.
  • Storage Instruction:
  • Store at 4°C. For long term storage store at-20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product is for research use only. Not for use in diagnostics or therapeutics.
  • Applications
  • Blocking
  • Application Image
  • Blocking
  • Gene Information
  • Entrez GeneID:
  • 1432
  • Protein Accession#:
  • NP_620581;Q16539
  • Gene Name:
  • MAPK14
  • Gene Alias:
  • CSBP1,CSBP2,CSPB1,EXIP,Mxi2,PRKM14,PRKM15,RK,SAPK2A,p38,p38ALPHA
  • Gene Description:
  • mitogen-activated protein kinase 14
  • Gene Summary:
  • The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • Csaids binding protein,MAP kinase Mxi2,MAX-interacting protein 2,cytokine suppressive anti-inflammatory drug binding protein,p38 MAP kinase,p38 mitogen activated protein kinase,p38alpha Exip,stress-activated protein kinase 2A
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