TLR2 monoclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of TLR2 monoclonal antibody (Cat # MAB8719) at 1 : 500 dilution. HeLa whole cell lysate 40 ug. Predicted band size : 90 KDa. Observed band size : 100 KDa.
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of TLR2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus residues of human TLR2.
Host
Mouse
Reactivity
Human
Specificity
This antibody is specific to TLR2.
Form
Liquid
Purification
Protein G purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:100-1:2000)
ELISA (1:5000-1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TLR2 monoclonal antibody (Cat # MAB8719) at 1 : 500 dilution. HeLa whole cell lysate 40 ug. Predicted band size : 90 KDa. Observed band size : 100 KDa.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TLR2
Entrez GeneID
7097GeneBank Accession#
NM_003264.3Gene Name
TLR2
Gene Alias
CD282, TIL4
Gene Description
toll-like receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq
Other Designations
toll/interleukin 1 receptor-like 4
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Interactome
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Pathway
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Disease
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