CSF3R monoclonal antibody, clone S-1374
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant CSF3R.
Immunogen
Recombinant MBP fusion protein corresponding to human CSF3R.
Host
Mouse
Reactivity
Human
Specificity
This antibody is reactive with GSF3R and does not cross-react with MBP or BSA.
Form
Lyophilized
Isotype
IgG2a, kappa
Recommend Usage
Western Blot (1-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 10 mM PBS, pH 7.2
Storage Instruction
Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CSF3R
Entrez GeneID
1441Gene Name
CSF3R
Gene Alias
CD114, GCSFR
Gene Description
colony stimulating factor 3 receptor (granulocyte)
Omim ID
138971Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq
Other Designations
CD114 antigen|OTTHUMP00000009703|OTTHUMP00000009704|OTTHUMP00000009705|colony stimulating factor 3 receptor|granulocyte colony stimulating factor receptor
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