Mouse monoclonal antibody raised against native FN1.
Native purified human FN1 from A8387 fibrosarcoma cells.
Chicken, Guinea pig, Human, Rabbit, Rat
This antibody is specific to extradomain A (EDA) sequence of a cellular fibronectin and recognizes thus only the cellular fibronectin. Clone DHI has been shown to specifically block chondrocyte condensation in chicken embryos. The monoclonal antibody DH1 recognizes only cellular form of Fibronectin.
The optimal working dilution should be determined by the end user.
In PBS (1% BSA, 0.09% sodium azide)
Store at 4°C.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq