Mouse monoclonal antibody raised against full length native CD14.
Native purified human CD14.
Theoretical MW (kDa):
This antibody reacts with CD14, a 53-55 KDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. This antibody MEM-15 also reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.
The optimal working dilution should be determined by the end user.
In PBS, pH 7.4 (15 mM sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq