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BIOtech
BULK-new

KIT monoclonal antibody, clone 57A5

  • Catalog # : MAB3412
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native KIT.
  • Immunogen:
  • Native purified KIT from human MO7e tumor cells.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Recognizes epitope 2 of the CD117 molecule, approximately 150 KDa in size.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
  • Storage Instruction:
  • Store at 4°C.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Flow Cytometry
  • 5 X 105 cultured HEL and HPB-MLT cells were washed and incubated 45 minutes on ice with 80 uL of KIT monoclonal antibody, clone 57A5 (Cat # MAB3412) at 5 ug/mL.
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 3815
  • Gene Name:
  • KIT
  • Gene Alias:
  • C-Kit,CD117,PBT,SCFR
  • Gene Description:
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Gene Summary:
  • This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • mast/stem cell growth factor receptor,proto-oncogene tyrosine-protein kinase Kit,soluble KIT variant 1
  • Interactome
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