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BIOtech
BULK-new

AGER monoclonal antibody, clone YK-2B4

  • Catalog # : MAB10578
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant AGER.
  • Immunogen:
  • Recombinant protein corresponding to excellular domain of human AGER.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 46-54
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A-Sepharose chromatography
  • Concentration:
  • 1.0 mg/mL
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM HEPES, pH 7.5, 150 mM NaCl (50% glycerol, 0.1 mg/mL BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of AGER expression in AGER/HEK 293 (1), and HEK293 (2) cell lines
  • Flow Cytometry
  • Flow Cytometry
  • Flow Cytometry analysis of AGER in AGER/HEK 293, and HEK293 cell lines.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 177
  • Gene Name:
  • AGER
  • Gene Alias:
  • MGC22357,RAGE
  • Gene Description:
  • advanced glycosylation end product-specific receptor
  • Gene Summary:
  • This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000029155,OTTHUMP00000029156,advanced glycosylation end product-specific receptor RAGE3,advanced glycosylation end product-specific receptor variant sRAGE1,advanced glycosylation end product-specific receptor variant sRAGE2,receptor for advanced
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