AXL monoclonal antibody, clone 7E10
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis using AXL monoclonal antibody, clone 7E10 (Cat # MAB10498) against extracellular domain of human AXL (aa 19-444).
Immunofluorescence
Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with AXL-hIgGFc using AXL monoclonal antibody, clone 7E10 (Cat # MAB10498)(green), showing cytoplasmic and membrane localization. Blue: DRAQ5 fluorescent DNA dye.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant AXL.
Immunogen
Recombinant hIgGFc tag fusion protein corresponding to extracellular fragment of human AXL.
Host
Mouse
Theoretical MW (kDa)
97.4
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using AXL monoclonal antibody, clone 7E10 (Cat # MAB10498) against extracellular domain of human AXL (aa 19-444).Immunofluorescence
Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with AXL-hIgGFc using AXL monoclonal antibody, clone 7E10 (Cat # MAB10498)(green), showing cytoplasmic and membrane localization. Blue: DRAQ5 fluorescent DNA dye.Enzyme-linked Immunoabsorbent Assay
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Gene Info — AXL
Entrez GeneID
558Gene Name
AXL
Gene Alias
JTK11, UFO
Gene Description
AXL receptor tyrosine kinase
Omim ID
109135Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
AXL transforming sequence/gene|oncogene AXL
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Interactome
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Disease
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