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Last updated: 2015/8/30
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CDK7 monoclonal antibody, clone 3E3

  • Catalog # : MAB0830
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant CDK7.
  • Immunogen:
  • Recombinant His/ABD fusion protein corresponding to amino acids 136-346 of human CDK7.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Western Blot (1:2000)
    Immunoprecipitation (1 ul)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Immunoblot analysis of cell lysates. Lane 1 : HeLa cell lysate. Lane 2 : Jurkat T cell lysate. Lane 3 : SK-N-MC cell lysate. Lane 4 : K-562 cell lysate.
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1022
  • Gene Name:
  • CDK7
  • Gene Alias:
  • CAK1,CDKN7,MO15,STK1,p39MO15
  • Gene Description:
  • cyclin-dependent kinase 7
  • Gene Summary:
  • The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq
  • Other Designations:
  • 39 KDa protein kinase,Cdk-activating kinase,cell division protein kinase 7,cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase),homolog of Xenopus MO15 Cdk-activating kinase,kinase subunit of CAK,serine/threonine kinase stk1,ser
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