GLCE (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of GLCE transfected lysate using rabbit polyclonal anti-GLCE and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-GLCE.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-GLCE (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-GLCE (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — GLCE
Entrez GeneID
26035Gene Name
GLCE
Gene Alias
HSEPI, KIAA0836
Gene Description
glucuronic acid epimerase
Gene Ontology
HyperlinkGene Summary
Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).[supplied by OMIM
Other Designations
D-glucuronyl C5-epimerase|UDP-glucuronic acid epimerase|glucuronyl C5-epimerase|heparan sulfate epimerase|heparin/heparan sulfate-glucuronic acid C5-epimerase
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Interactome
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Pathway
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Disease
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